Infants with congenital Zika virus syndrome suffer serious visual impairment


There is a broad collection of anomalies now known as congenital Zika syndrome (CZS). Some of the most serious are ophthalmologic. Two articles evaluated visual function among infants with suspected and confirmed CZS. Both studies found that while about 40 percent of patients had ocular abnormalities, 100 percent of children tested had visual impairment. Thus, cortical visual impairment might be the most common cause of blindness among children with CZS.

CRISPR sheds light on rare pediatric bone marrow failure syndrome


Using the gene editing technology CRISPR, scientists have shed light on a rare, sometimes fatal syndrome that causes children to gradually lose the ability to manufacture vital blood cells. The research suggests new lines of investigation into how to treat this condition — dyskeratosis congenita — which is characterized by shortened telomeres. Short telomeres lead to progressive DNA damage that accumulates over time.

Outcomes for long QT syndrome patients treated at specialty center are better


Sudden cardiac death, and episodes of fainting and seizures from long QT syndrome are significantly lower than previously thought when patients are diagnosed and treated at a specialty center dedicated to the treatment of genetic heart rhythm diseases, according to research. This is one of the largest studies of long QT syndrome patients — people who have an inherited heart rhythm condition that can potentially cause fast and chaotic heartbeats — evaluated and treated at a single center to analyze these outcomes.