Scientists construct first predictive model of inflammatory bowel disease


An in-depth, multi-omics approach to characterizing the immune component of inflammatory bowel disease (IBD) has been revealed by researchers. These results provide new insights into the biologic networks involved in IBD with potential to identify new targets and eventually novel interventions for the treatment of patients living with IBD.

Understanding how omega-3 dampens inflammatory reactions


Omega-3 fatty acids, which we primarily get through eating fatty fish, have long been thought to be good for our health. Many dietary studies have suggested that high intake is associated with a reduced risk of various disorders. Clinical trials have also shown beneficial anti-inflammatory effects in patients taking omega-3 supplements.

Novel stem cell-derived model created of inflammatory neurological disorder


An international team of scientists, has created a human stem cell-based model of a rare, but devastating, inherited neurological autoimmune condition called Aicardi-Goutieres Syndrome (AGS). In doing so, the team was able to identify unusual and surprising underlying genetic mechanisms that drive AGS and test strategies to inhibit the condition using existing drugs.

Antibiotics taken late in pregnancy can increase risk for inflammatory bowel diseases in offspring


When mice that are genetically susceptible to developing inflammatory bowel disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an inflammatory condition of the colon that resembles human IBD, report scientists.