A detailed study of how domains within the Cas9 protein move when the molecule binds to DNA has allowed scientists to locate the protein that monitors the fidelity of binding between the Cas9 single-guide RNA and its DNA target. The researchers then tweaked this domain to boost specificity, creating the highest fidelity Cas9 protein to date.
Emotional responses to failure rather than cognitive ones are more effective at improving people’s results for the next time they tackle the next related task, new research indicates.
Researchers have discovered how oxygen-deprived tumors survive body’s immune response, explains a new report.
A new study demonstrates the potential of wearable technology as a social-skills aid for children with autism spectrum disorder.
Students who took part in a program that taught scientific argumentation learned the concepts better than their peers who did not, a study concludes.
Half the people who completed a 10-week community running program aimed at helping them quit smoking were successful in their attempt. Many others reduced their smoking, and saw their mental health improve.
A new class of enzymes has been discovered in hundreds of bacterial species, including some that cause disease in humans and animals. The discovery provides new insights into how bacteria invade their hosts.
Researchers have identified two independent pathways in the fly brain that are integrated to allow successful navigation during flight. The study combined a flight simulator designed for flies with imaging of active neurons to show that landmark locations are processed separately in the fly brain from self-motion.
Working at a health center in rural Uganda, researchers have demonstrated for the first time the potential of using a low-cost, routinely available rapid diagnostic test to distinguish between severe and uncomplicated malaria in children.
Researchers have discovered how by-products of the digestion of dietary fiber by gut microbes act as the right fuel to help intestinal cells maintain gut health.