Cell model of the brain provides new knowledge on developmental disease


By reprogramming skin cells into nerve cells, researchers are creating cell models of the human brain. In a new study, the researchers describe how cells from patients with the severe developmental disease lissencephaly differ from healthy cells. The method can provide vital new knowledge on difficult-to-study congenital diseases.

Decreased glucose metabolism in medial prefrontal areas is associated with nutritional status in patients with prodromal and early Alzheimer's disease


A new study shows that hypometabolism in the medial prefrontal areas is specifically associated with Alzheimer’s disease-related nutritional problems, and decrease in fat mass may have a key role.

Scientists construct first predictive model of inflammatory bowel disease


An in-depth, multi-omics approach to characterizing the immune component of inflammatory bowel disease (IBD) has been revealed by researchers. These results provide new insights into the biologic networks involved in IBD with potential to identify new targets and eventually novel interventions for the treatment of patients living with IBD.