Children diagnosed with inflammatory bowel disease have an increased risk of cancer, especially gastrointestinal cancers, both in childhood and later in life, finds a study.
The growth of certain aggressive brain tumors can be halted by cutting off their access to a signaling molecule produced by the brain’s nerve cells, according to a new study.
Opening up a new pathway to fight cancer, researchers have found a way to target an enzyme that is crucial to tumor growth while also blocking the mechanism that has made past attempts to target that enzyme resistant to treatment. Researchers were able to use this finding to develop a drug that successfully inhibits tumor growth of melanoma as well as pancreatic and colorectal cancer in mice.
Researchers have discovered how oxygen-deprived tumors survive body’s immune response, explains a new report.
Scientists have discovered that a combination of artemisinin, which is a potent anti-malarial drug, and aminolaevulinic acid, which is a photosensitizer, could kill colorectal cancer cells and suppress tumor growth more effectively than administering artemisinin alone. This novel combination therapy could also have fewer side effects.
It had already been known that the enzyme known as phosphatidic acid phosphatase plays a crucial role in regulating the amount of fat in the human body. Controlling it is therefore of interest in the fight against obesity. But scientists have now found that getting rid of the enzyme entirely can increase the risk of cancer, inflammation and other ills.
Researchers have not only untangled an unusual wiring system that cancer cells use for carbohydrate metabolism, but also identified a natural compound that appears to selectively shut down this system in laboratory studies.
Researchers found a possible new treatment for aggressive triple receptor-negative breast cancer.
Detecting cancer could be as easy as a home pregnancy test. Current test strip designs are not sensitive enough, but a new design with platinum-coated gold nanoparticles could make cheap and simple test strip detection a reality.
In an innovative approach to colorectal cancer (CRC) prevention and treatment, scientists are studying ways to replace missing metabolites in patients prone to gut inflammation and CRC. A new study describes how administration of histamine-producing gut microbes to mice lacking the enzyme histidine decarboxylase (HDC) reduced inflammation and tumor formation. These results suggest that alteration of the gut microbiome with probiotics may become a new preventative or therapeutic strategy for patients at risk for inflammatory bowel disease (IBD)-associated CRC.